CÁC THÀNH TỰU CHÍNH
Function: To organize the deployment of applications and research in advanced biomedical materials and other related fields.
Missions:
- To develop technology and organize the implementation of research results into practice, applying biomedical materials in fields such as the environment, agriculture, medicine and pharmacy, food, and other related areas under the Institute's registration for scientific and technological activities.
- To conduct basic research in the field of biomedical materials.
- To train high-level human resources in specialized fields licensed to the Institute and consistent with the Center’s functions.
- To engage in domestic and international cooperation in line with agreements signed by the Institute.
Main Research Directions:
- Fabrication and development of electrochemical biosensor systems for applications in biomedicine, environmental monitoring, and food safety control; magnetic nanomaterials for biomedical applications; nano-structured drug delivery systems for cancer prevention and treatment.
- Application of nanotechnology in the production of functional foods, in industry, and in aquaculture.
Contact Information of the Center Director:
- Academic Title, Full Name: Assoc. Prof. Dr., Senior Researcher. Ha Phuong Thu
- Office Address: Room: 331, Building: A2
- Mobile Phone: 0988 165 677
- Email: thuhp@ims.(*) - Note: Replace (*) = vast.ac.vn
MEMBERS
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No
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Academic title/Degree/Full Name
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Tenure/ Contract
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Email
Note: Replace (*) = vast.ac.vn
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| 1 |
Assoc. Prof. Ha Phuong Thu
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Tenure
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thuhp@ims. (*)
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2
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Dr. Pham Hong Nam
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Tenure
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namph@.ims. (*)
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| 3 |
Dr. Vuong Thi Kim Oanh
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Tenure
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oanhvtk@ims. (*)
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4
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Dr. Mai Thi Thu Trang
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Tenure
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trangmtt@ims. (*)
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5
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Dr. PharmD. Phan Ke Son
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Tenure
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sonpk@ims. (*)
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6
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MSc. Nguyen Hoai Nam
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Tenure
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namnh@ims. (*)
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7
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MSc. Ngo Thanh Hieu
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Tenure
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nthieu@ims. (*)
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8
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PharmD. Đong Thị Nham
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Contract
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KEY ACHIEVEMENTS
The (Fucoidan - Ginseng - Curcumin) nanocomplex called FGC nanocomplex was developed due to an order project from CVI Cosmetic Pharmaceutical Joint Stock Company and a project supporting research staff of the Institute of Materials Science. Associate Professor, PhD. Ha Phuong Thu and her colleagues successfully conducted research and transferred FGC nanocomplex materials to CVI Pharmaceutical and Cosmetic Joint Stock Company. The FGC nanocomplex has been developed by CVI Pharmaceutical and Cosmetic Joint Stock Company into the CumarGold Kare product on the market today. CumarGold Kare functional food is the first and only product containing the FGC nanocomplex. Since 2017, after the success of the project sponsored by Innofund Fund (MS: VIE 12 047 11/AP/001/FINANCING AGREEMENT/003-W1 12/2016-12/2017), along with the support of the Academy of Sciences studying materials, Associate Professor, PhD. Ha Phuong Thu, has continued to upgrade the production scale of FGC ingredients up to 120 kg/month, equivalent to 20,000 boxes of CurmaGold Kare products. Up to now, the product is continuing to be transferred to CVI Pharmaceutical and Cosmetic Joint Stock Company with an amount of about 10,000 boxes per month. The FGC nanocomplex in CumarGold Kare functional food contains ingredients that can maximize effectiveness for cancer patients: kill tumour cells, reduce tumor size, prevent metastasis, and prevent cancer. side effects. Used in prevention, improving physical condition, and preventing exhaustion for cancer patients after chemotherapy and radiotherapy, received very positive feedback from cancer patients. This is especially meaningful when the number of cancer cases is increasing in Vietnam and around the world.
The FGC nanocomplex production technology process has been granted Patent No. 22424 by the National Office of Intellectual Property in 2019.
Fig. 1. (a) CumarGold Kare Functional Food Products, and (b) Technology transfer ceremony of FGC nano-complex products to CVI . Cosmetics Pharmaceutical Joint Stock Company
SELECTED PUBLICATIONS
Scientific Publications
- Ke Son Phan, Bich Thuy Doan, Yiqian Wang, Thi Thu Huong Le, Thi Thu Trang Mai, Hong Nam Pham, Ha Bao Hung Bui, Le Hang Dang, Ngoc Quyen Tran, Phuong Thu Ha*, Harnessing for quantitative MRI, bioluminescence, chemo-magnetic hyperthermia, and near-infrared optical imaging of magnetic nanotheranostic for in vivo passive targeted monitoring in colorectal cancer models, Biomaterials Science, 13, 5402-5421 (2025).
- Ke Son Phan, Huu Nghi Do, Bich Thuy Doan, Thi Thu Huong Le, Thi Thu Trang Mai, Quynh Bao Ngoc Nguyen, Thi Nham Dong, Bao Hung Bui Ha, Viet Dung Dang, Le Hang Dang, Ngoc Quyen Tran, Phuong Thu Ha*, The Influence of Cyanine 5.5 and Doxorubicin on Cell Cycle Arrest, Magnetic Resonance, and Near-Infrared Fluorescence Optical Imaging for Fe3O4-Encapsulated PLA-TPGS Nanoparticles, ChemMedChem 20, e202400586 (2025).
- Thi Thu Huong Le, Ke Son Phan, Bich Thuy Doan, Thi Thu Trang Mai, Ha Bao Hung Bui, Hong Nam Pham, Thi Dieu Thuy Ung, Yiqian Wang, Ngoc Quyen Tran, Le Hang Dang, Phuong Thu Ha*, Different conjugates of Fe3O4 nanoparticles, drug, and dye: optical and magnetic properties for in vivo bimodal imaging, RSC Advances, 15, 9644-9656 (2025).
- Phan Ke Son, Le Thi Thu Huong, Nguyen Thi Minh, Mai Thi Thu Trang, Hoang Phuong Ha, To Xuan Thang, Thanh Trung Nguyen, Kim Dang Pham, Ha Phuong Thu*, Co-delivery of Doxycycline, Florfenicol and Silver Nanoparticles using Alginate/Chitosan Nanocarriers, ChemistrySelect, 7, 33, e202201954 (2022).
- Luu Huu Nguyen, Truong Hai Bang, Nguyễn Hoài Nam, Hà Phương Thư, Đỗ Hùng Mạnh, Le The Tam, Dinh Van Tuan, Phan Thi Hong Tuyet, Pham Thanh Phong, Pham Hong Nam*, Impact of the correlation between doping content and ions distribution in Gd-doped CoFe2O4 nanoparticles on their magnetic properties and heating efficiency, Journal of Materials Science 59, 10793–10809 (2024).
- Luu Huu Nguyen, Nguyen Hoai Nam, Le The Tam, Dinh Van Tuan, Nguyen Xuan Truong, Nguyen Van Quynh, Phan Thi Hong Tuyet, Ha Phuong Thu, Do Hung Manh, Pham Thanh Phong, Pham Hong Nam*, Effect of Gd substitution on structure, optical and magnetic properties, and heating efficiency of Fe3O4 nanoparticles for magnetic hyperthermia applications, Journal of Alloys and Compounds 968, 172205 (2023).
- Pham Hong Nam*, Nguyen Xuan Phuc, Do Hung Manh, Do Khanh Tung, Nguyen Van Quynh, Nguyen Hoai Nam, Phan Ke Son, Ta Ngoc Bach, Pham Thanh Phong, Physical characterization and heating efficacy of chitosan-coated cobalt ferrite nanoparticles for hyperthermia application, Physica E: Low-dimensional Systems and Nanostructures, 134, 114862 (2021).
- Oanh Vuong TK*, Le TT, Do HD, Nguyen XT, Nguyen XC, Vu TT, Le TL, Tran DL. PMAO-assisted thermal decomposition synthesis of high-stability ferrofluid based on magnetite nanoparticles for hyperthermia and MRI applications. Chem. Phys., 245, 122762 (2020).
- Vuong Thi Kim Oanh*, Le Thi Hong Phong, Nguyen Duc Van, Mai Thi Thu Trang, Ha Phuong Thu, Nguyen Xuan Truong, Nguyen Xuan Ca, Dinh Chi Linh, Pham Hong Nam, Do Hung Manh, Magnetic, Biocompatible CoFe2O4/Fe3O4 Core/Shell Nanoparticles: Designing And Improved Hyperthermia Properties, Journal of Nanoparticle Research, 25, 212 (2023).
- Vuong Thi Kim Oanh*, L. T. H. Phong, N. H. A. Thu, N. X. Truong, P. H. Nam, N. N. P. Vy, N. T. Luyen, V. T. B. Ngoc, Enhanced Magnetic Hyperthermia and MRI Performance of CoFe2O4/MnFe2O4 Core/Shell Nanostructures, Journal of Electronic Materials, Volume 54, pages 2065–2079, (2025).
Intellectual Property
- Patent: “Method for microencapsulating Curcumin using Fucoidan extracted from brown seaweed (Laminaria japonica Aresch) and Saponin from Panax notoginseng root (Panax notoginseng (Burk.) F. H. Chen) and the nano-system (Fucoidan-Ginseng-Curcumin) obtained by this method,” Patent No. 22424, year 2019; author: Ha Phuong Thu.
- Patent: “Method for producing fertilizer based on porous hydroxyapatite material carrying macro and micro elements and the fertilizer obtained by this method,” Patent No. 25414, year 2020. Authors: Ha Phuong Thu, Nguyen Hoai Nam, Phan Ke Son.
- Patent: “Device for removing ethylene gas from the preservation environment of fresh fruits and vegetables,” Patent No. 30332, year 2021. Authors: Pham Hong Nam, Nguyen Hoai Nam, Nguyen Xuan Truong.
- Patent: “Method for preparing a combined antibiotic nano-system for poultry and this combined antibiotic nano-system,” Patent No. 33759, year 2022. Authors: Ha Phuong Thu, Le Thi Thu Huong, Phan Ke Son, Tran Thi Lan Anh.
- Patent: “Method for producing a multifunctional nanomaterial based on PLA-TPGS copolymer simultaneously carrying doxorubicin and magnetic iron oxide nanoparticles,” Patent No. 40854, year 2024. Authors: Phan Ke Son, Ha Phuong Thu, Le Thi Thu Huong, Mai Thi Thu Trang, Do Huu Nghi, Bui Thuc Quang.
FACILITIES
- High Power Alternating Magnetic Field Generator Model UHF-20A - Feature: Research the heat generation characteristics of magnetic nanoparticles.
- Microwave system Uwave -1000 - Feature: Synthesis of magnetic nanomaterials.